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IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

产品编号 TMPJ-01099
别名: interleukin-15 receptor subunit α, IL15RA, interleukin-15 receptor subunit alpha, IL-15RA, IL-15R-α, α, MGC104179, CD215 antigen, IL-15 receptor subunit α, CD215, IL-15 receptor subunit alpha, IL-15R-alpha, alpha, interleukin 15 receptor

Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.

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IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 现货
20 μg ¥ 1,880 5日内发货
50 μg ¥ 3,470 5日内发货
100 μg ¥ 5,220 5日内发货
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产品目录号及名称: IL-15RA Protein, Human, Recombinant (hFc, Human Cells) (TMPJ-01099)
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生物活性
技术参数
产品性质
生物活性 Measured by its ability to block human IL-15-induced proliferation of CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.35-3.5 ng/ml. (QC verified)

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产品描述 Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.
种属 Human
表达系统 HEK293 Cells
标签 C-hFc
蛋白编号 Q13261-3
别名 interleukin-15 receptor subunit α, IL15RA, interleukin-15 receptor subunit alpha, IL-15RA, IL-15R-α, α, MGC104179, CD215 antigen, IL-15 receptor subunit α, CD215, IL-15 receptor subunit alpha, IL-15R-alpha, alpha, interleukin 15 receptor
氨基酸序列 Ile31-Thr172
蛋白构建 Ile31-Thr172
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.

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分子量 60-75 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.

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Keywords

IL-15RA Protein, Human, Recombinant (hFc, Human Cells) interleukin-15 receptor subunit α IL15RA CD-215 interleukin-15 receptor subunit alpha IL-15RA IL-15R-α α MGC104179 CD 215 CD215 antigen IL-15 receptor subunit α CD215 IL-15 receptor subunit alpha MGC 104179 IL-15R-alpha alpha MGC-104179 interleukin 15 receptor recombinant recombinant-proteins proteins protein

 

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