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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CARD12 Polyclonal Antibody

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货号 TMAB-03624

Anti-CARD12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CARD12。Anti-CARD12 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-CARD12 Polyclonal Antibody

Anti-CARD12 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03624

Anti-CARD12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CARD12。Anti-CARD12 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-CARD12 Polyclonal Antibody is a Rabbit antibody targeting CARD12. Anti-CARD12 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cytoplasm, cytosol. Note=Cytoplasmic filaments.
组织特异性Isoform 2 is expressed ubiquitously, although highly expressed in lung and spleen. Isoform 1 is highly expressed in lung, followed by leukocytes especially monocytes, lymph node, colon, brain, prostate, placenta, spleen, bone marrow and fetal liver. Isoform 4 is only detected in brain.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景NLR family CARD domain-containing protein 4 is a protein that in humans is encoded by the NLRC4 gene. NLRC4 is best associated with triggering formation of the inflammasome. Unlike NLRP3, certain inflammasome-dependent functions of NLRC4 may be carried out independently of the inflammasome scaffold ASC. Human Ced4 homologs include APAF1, NOD1 (CARD4), and NOD2 (CARD15). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CARD12
抗原种属
Human
基因名称
NLRC4
基因ID
58484
蛋白名称
NLR family CARD domain-containing protein 4
Uniprot ID
Q9NPP4
功能
Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis.
化学信息
分子量Theoretical: 116 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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