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Anti-PSGL-1/CD162 Polyclonal Antibody

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货号 TMAB-01588

别名 selectin P ligand, PSGL-1, PSGL1, CLA, CD162

Anti-PSGL-1/CD162 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PSGL-1/CD162。Anti-PSGL-1/CD162 Polyclonal Antibody 可用于 WB。

Anti-PSGL-1/CD162 Polyclonal Antibody

Anti-PSGL-1/CD162 Polyclonal Antibody

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货号 TMAB-01588 别名 selectin P ligand, PSGL-1, PSGL1, CLA, CD162

Anti-PSGL-1/CD162 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PSGL-1/CD162。Anti-PSGL-1/CD162 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-PSGL-1/CD162 Polyclonal Antibody is a Rabbit antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Polyclonal Antibody can be used in WB.
别名selectin P ligand, PSGL-1, PSGL1, CLA, CD162
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
验证活性
Sample:
Bone (Mouse) Lysate at 40 μg
Primary: Anti-PSGL-1/CD162 (TMAB-01588) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kDa
Observed band size: 41 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Expressed on neutrophils, monocytes and most lymphocytes.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011].
抗原信息
免疫原
KLH conjugated synthetic peptide: human PSGL-1/CD162
抗原种属
Human
基因名称
SELPLG
基因ID
6404
蛋白名称
P-selectin glycoprotein ligand 1
Uniprot ID
Q14242
研究领域
Cell adhesion molecules,Adhesion
功能
A SLe(x)-type glycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. PSGL1 is critical for the initial leukocyte capture.
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

PSGL 1CD-162CD 162
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