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Anti-CD31/PECAM-1 Antibody (1O74) 是一种 Rabbit 抗体,靶向 CD31/PECAM-1。Anti-CD31/PECAM-1 Antibody (1O74) 可用于 FCM。
Anti-CD31/PECAM-1 Antibody (1O74) 是一种 Rabbit 抗体,靶向 CD31/PECAM-1。Anti-CD31/PECAM-1 Antibody (1O74) 可用于 FCM。
产品描述 | Anti-CD31/PECAM-1 Antibody (1O74) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (1O74) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 1O74 |
交叉反应 | Mouse |
验证活性 | Flow cytometric analysis of Mouse PECAM1(CD31) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse PECAM1(CD31) , then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
应用 | FCM |
推荐剂量 | FCM: 1:25-1:100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD31/PECAM-1 (rM CD31/PECAM-1; TMPY-01619; NP_033868.3; Met1-Lys590). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. |
偶联 | Unconjugated |
其他可选修饰符 | APC/FITC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Mouse CD31/PECAM-1 Protein (TMPY-01619) |
抗原种属 | Mouse |
研究领域 | Hemangioblast Markers, ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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