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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CLEC7A Polyclonal Antibody

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货号 TMAB-00448

别名 β-glucan receptor, Dectin-1, DECTIN1, DC-associated C-type lectin 1, CLECSF12, CD369, CANDF4, BGR, Beta-glucan receptor

Anti-CLEC7A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CLEC7A。Anti-CLEC7A Polyclonal Antibody 可用于 WB。

Anti-CLEC7A Polyclonal Antibody

Anti-CLEC7A Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-00448 别名 β-glucan receptor, Dectin-1, DECTIN1, DC-associated C-type lectin 1, CLECSF12, CD369, CANDF4, BGR, Beta-glucan receptor

Anti-CLEC7A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CLEC7A。Anti-CLEC7A Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-CLEC7A Polyclonal Antibody is a Rabbit antibody targeting CLEC7A. Anti-CLEC7A Polyclonal Antibody can be used in WB.
别名β-glucan receptor, Dectin-1, DECTIN1, DC-associated C-type lectin 1, CLECSF12, CD369, CANDF4, BGR, Beta-glucan receptor
Ig Type
IgG
反应种属
Mouse (predicted:Rat)
验证活性
Sample:
Lane 1: Mouse Blood cell lysates
Primary: Anti-CLEC7A (TMAB-00448) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 28 kDa
Observed band size: 42,27,21 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type II membrane protein.
组织特异性Detected in dendritic cells, in paracortical and medullary regions of lymph nodes, and in spleen red pulp and white pulp.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse CLEC7A
抗原种属
Mouse
基因名称
CLEC7A
基因ID
56644
蛋白名称
C-type lectin domain family 7 member A
Uniprot ID
Q6QLQ4
研究领域
Macrophage / Inflamm.
功能
Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).
化学信息
分子量Theoretical: 28 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

DECTIN 1CLECSF-12CLECSF 12CD-369CD 369CANDF-4CANDF 4b-glucan receptor
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