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AGA (Aspartylglucosaminidase) is an amidohydrolase enzyme involved in the catabolism of N-linked oligosaccharides of glycoproteins. This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. Diseases associated with AGA include Aspartylglucosaminuria and Lysosomal Storage Disease. An important paralog of this gene is ASRGL1.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 683 | 6-8日内发货 | |
| 10 μg | ¥ 1,130 | 6-8日内发货 | |
| 20 μg | ¥ 1,930 | 5日内发货 | |
| 50 μg | ¥ 4,430 | 5日内发货 |
| 生物活性 | Measured by its ability to hydrolyze the AspAMC. The specific activity is >300 pmol/min/μg. |
| 产品描述 | AGA (Aspartylglucosaminidase) is an amidohydrolase enzyme involved in the catabolism of N-linked oligosaccharides of glycoproteins. This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. Diseases associated with AGA include Aspartylglucosaminuria and Lysosomal Storage Disease. An important paralog of this gene is ASRGL1. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-His |
| 蛋白编号 | CAA39029.1 |
| 别名 | GA,ASRG,aspartylglucosaminidase,AGU |
| 蛋白构建 | A DNA sequence encoding the human AGA (CAA39029.1) (Met1-Ile346) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Ser 24 |
| 蛋白纯度 | > 95 % as determined by SDS-PAGE |
| 分子量 | 36.1 kDa (predicted); 47, 29, 23 and 20 kDa (reducing condition, due to glycosylation) |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 研究背景 | AGA (Aspartylglucosaminidase) is an amidohydrolase enzyme involved in the catabolism of N-linked oligosaccharides of glycoproteins. This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. Diseases associated with AGA include Aspartylglucosaminuria and Lysosomal Storage Disease. An important paralog of this gene is ASRGL1. |