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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Thioredoxin Antibody (4X610)

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货号 TMAB-13511

Anti-Thioredoxin Antibody (4X610) 是一种 Rabbit 抗体，靶向 Thioredoxin。Anti-Thioredoxin Antibody (4X610) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP。

Anti-Thioredoxin Antibody (4X610)

Anti-Thioredoxin Antibody (4X610)

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Rating icon 还可以
货号 TMAB-13511

Anti-Thioredoxin Antibody (4X610) 是一种 Rabbit 抗体，靶向 Thioredoxin。Anti-Thioredoxin Antibody (4X610) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Thioredoxin Antibody (4X610) is a Rabbit antibody targeting Thioredoxin. Anti-Thioredoxin Antibody (4X610) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP.
Ig Type
IgG
克隆号
4X610
反应种属
Human
应用WBIHC-PIHC-FrICC/IFIFIP
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Secreted. Note=Secreted by a leaderless secretory pathway. Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.
抗原信息
免疫原
A synthesized peptide: human Thioredoxin
抗原种属
Human
基因名称
TXN
基因ID
7295
蛋白名称
Thioredoxin
Uniprot ID
P10599
功能
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
化学信息
分子量Theoretical: 12 kDa. Actual: 12 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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