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Anti-CACNB3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CACNB3。Anti-CACNB3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-CACNB3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CACNB3。Anti-CACNB3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-CACNB3 Polyclonal Antibody is a Rabbit antibody targeting CACNB3. Anti-CACNB3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 组织特异性 | Expressed mostly in brain, smooth muscle and ovary. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Voltage-dependent calcium channels are essential for the release of neurotransmitters. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an Alpha1 subunit, a Beta subunit, a Beta subunit and an Alpha2 Gamma subunit. The Beta subunit is encoded by four genes, designated Beta1-Beta4, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the Beta subunit. L-type Ca++ CP Beta3, also known as CACNB3 (Calcium channel voltage-dependent subunit beta 3), CACNLB3 or CAB3, is a 484 amino acid protein that contains one SH3 domain and is expressed in ovary, brain and smooth muscle. Functioning as one of the four components of the Beta subunit, L-type Ca++ CP Beta 3 increases the peak calcium current in voltage-dependent calcium channels, thereby shifting the voltage dependencies of activation and inactivation and controlling G protein inhibition and Beta membrane targeting. Two isoforms of L-type Ca++ CP Beta3 exist due to alternative splicing events. |
| 免疫原 | KLH conjugated synthetic peptide: human CACNB3 |
| 抗原种属 | Human |
| 基因名称 | CACNB3 |
| 基因ID | |
| 蛋白名称 | Voltage-dependent L-type calcium channel subunit beta-3 |
| Uniprot ID | |
| 功能 | The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. |
| 分子量 | Theoretical: 54 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |