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Anti-S6K1/RPS6KB1 Antibody (6S46)
还可以产品编号 TMAY-00251
Anti-S6K1/RPS6KB1 Antibody (6S46) 是一种 Mouse 抗体，靶向 S6K1/RPS6KB1。Anti-S6K1/RPS6KB1 Antibody (6S46) 可用于 ELISA。
Anti-S6K1/RPS6KB1 Antibody (6S46)
Anti-S6K1/RPS6KB1 Antibody (6S46)
还可以产品编号 TMAY-00251
Anti-S6K1/RPS6KB1 Antibody (6S46) 是一种 Mouse 抗体，靶向 S6K1/RPS6KB1。Anti-S6K1/RPS6KB1 Antibody (6S46) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-S6K1/RPS6KB1 Antibody (6S46) is a Mouse antibody targeting S6K1/RPS6KB1. Anti-S6K1/RPS6KB1 Antibody (6S46) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 6S46 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PS6K / RPS6KB1 (rh PS6K / RPS6KB1; TMPY-04540; P23443; Met1-Leu525). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | PS6K, also known as RPS6KB1, is a serine/threonine-protein kinase. It belongs to the RSK (ribosomal s6 kinase) family. Members of this family function in signal transduction. PS6K is an isoform of p70 ribosomal S6 kinase (S6K). S6K can be activated by mitogenic stimuli such as growth factors, insulin and cytokines. It phosphorylates the ribosomal protein S6. PS6K also phosphorylates other proteins such as elF4B, eEF2K and SKAR. It is a crucial effector of mTOR(rapamycin) signaling. PS6K is dissociated from the EIF3 complex and activated upon mitogenic stimulation, phosphorylation by the mammalian target of mTOR complex 1 (mTORC1). Its active form then phosphorylates and activates several substrates in the preinitiation complex, including the EIF2B complex and the cap-binding complex component EIF4B. PS6K also functions in cell proliferation, cell growth and cell cycle progression. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human PS6K / RPS6KB1 protein (TMPY-04540) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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