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Anti-ITGB4 Antibody (3G397) 是一种 Rabbit 抗体,靶向 ITGB4。Anti-ITGB4 Antibody (3G397) 可用于 WB,IHC。
Anti-ITGB4 Antibody (3G397) 是一种 Rabbit 抗体,靶向 ITGB4。Anti-ITGB4 Antibody (3G397) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-ITGB4 Antibody (3G397) is a Rabbit antibody targeting ITGB4. Anti-ITGB4 Antibody (3G397) can be used in WB,IHC. |
Ig Type | IgG |
克隆号 | 3G397 |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of Integrin beta 4 on Jurkat cells lysates using anti-Integrin beta 4 antibody at 1/500 dilution. Positive control: Line 1: A431, Line 2: A549. 2. Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-Integrin beta 4 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Integrin beta 4 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Integrin beta 4 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Integrin beta 4 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands, such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Integrin β4 (ITGB4), also known as CD104, is a 1,822 amino acid single-pass type I membrane protein belonging to the Integrin β chain family. Known to associate with Integrin α6, Integrin β4 functions as a receptor for Laminin and is predominantly expressed by epithelia. Integrin β4 exists as five alternatively spliced isoforms that are encoded by a gene located on human chromosome 17q25.1. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 210 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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