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IL-18 Protein, Human, Recombinant V2

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产品编号 TMPY-00277U

IL-18 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is Q14116.

IL-18 Protein, Human, Recombinant V2

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产品编号 TMPY-00277U

IL-18 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is Q14116.

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生物活性	Immobilized Human IL-18 at 5 μg/ml (100 μl/Well) on the plate. Dose response curve for Human IL-18BP, hFc Tag with the EC50 of 16.9 ng/ml determined by ELISA (QC Test). Human IL-18 R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human IL-18, No Tag with an affinity constant of 2.38 nM as determined in SPR assay (Biacore T200).
产品描述	IL-18 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is Q14116.
种属	Human
表达系统	E. coli
标签	Tag Free
蛋白编号	Q14116
别名	Interleukin 18,IL-1g,IL1F4,IL-18,IGIF
蛋白构建	Tyr37-Asp193
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	18.2 kDa (Predicted and reducing conditions)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in 20 mM PB, 250 mM NaCl, 50 mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.