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Anti-FAP1 Antibody (6P590)

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Anti-FAP1 Antibody (6P590)
产品编号 TMAC-01444
别名 SIMP, Seprase, FAPα, FAPalpha, FAPA, FAP, DPPIVA, DPPIV, APCE

Anti-FAP1 Antibody (6P590) 是一种 Rabbit 抗体,靶向 FAP1。Anti-FAP1 Antibody (6P590) 可用于 WB,IHC。

Anti-FAP1 Antibody (6P590)

Anti-FAP1 Antibody (6P590)

Rating icon 还可以
Anti-FAP1 Antibody (6P590)
产品编号 TMAC-01444 别名 SIMP, Seprase, FAPα, FAPalpha, FAPA, FAP, DPPIVA, DPPIV, APCE

Anti-FAP1 Antibody (6P590) 是一种 Rabbit 抗体,靶向 FAP1。Anti-FAP1 Antibody (6P590) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-FAP1 Antibody (6P590) is a Rabbit antibody targeting FAP1. Anti-FAP1 Antibody (6P590) can be used in WB,IHC.
别名SIMP, Seprase, FAPα, FAPalpha, FAPA, FAP, DPPIVA, DPPIV, APCE
Ig Type
IgG
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-FAP1 antibody. Counter stained with hematoxylin.
应用
推荐剂量
WB: 1:500-1000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景FAP (fibroblast activation protein) is a cell surface glycoprotein and serine protease that is expressed primarily in fetal mesenchymal tissues and epithelial cancer fibroblasts. In cancer, FAP functions to promote cellular proliferation. In embryonic development, FAP functions to remodel developing tissues. FAP acts as an integral membrane gelatinase composed of N-glycosylated proteolytically inactive subunits. FAP expression on chondrocyte membranes is upregulated by the combination of the cytokines IL-1 and OSM and has been shown to increase in osteoarthritic patients. This expression is co-localized with MMP-1and MMP-13 as well as CD44 (variants v3 and v7/8). Mice that lack all copies of the FAP gene have been found to be fertile and to have developmental defects or change in cancer susceptibility.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 95 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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