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Anti-FAP1 Antibody (6P590) 是一种 Rabbit 抗体,靶向 FAP1。Anti-FAP1 Antibody (6P590) 可用于 WB,IHC。
Anti-FAP1 Antibody (6P590) 是一种 Rabbit 抗体,靶向 FAP1。Anti-FAP1 Antibody (6P590) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-FAP1 Antibody (6P590) is a Rabbit antibody targeting FAP1. Anti-FAP1 Antibody (6P590) can be used in WB,IHC. |
别名 | SIMP, Seprase, FAPα, FAPalpha, FAPA, FAP, DPPIVA, DPPIV, APCE |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-FAP1 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | FAP (fibroblast activation protein) is a cell surface glycoprotein and serine protease that is expressed primarily in fetal mesenchymal tissues and epithelial cancer fibroblasts. In cancer, FAP functions to promote cellular proliferation. In embryonic development, FAP functions to remodel developing tissues. FAP acts as an integral membrane gelatinase composed of N-glycosylated proteolytically inactive subunits. FAP expression on chondrocyte membranes is upregulated by the combination of the cytokines IL-1 and OSM and has been shown to increase in osteoarthritic patients. This expression is co-localized with MMP-1and MMP-13 as well as CD44 (variants v3 and v7/8). Mice that lack all copies of the FAP gene have been found to be fertile and to have developmental defects or change in cancer susceptibility. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 95 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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