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Anti-IL-10RA Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL-10RA。Anti-IL-10RA Polyclonal Antibody 可用于 WB。
Anti-IL-10RA Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL-10RA。Anti-IL-10RA Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-IL-10RA Polyclonal Antibody is a Rabbit antibody targeting IL-10RA. Anti-IL-10RA Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Pig,Cow) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq]. |
| 免疫原 | KLH conjugated synthetic peptide: human IL-10RA |
| 抗原种属 | Human |
| 基因名称 | IL10RA |
| 基因ID | |
| 蛋白名称 | Interleukin-10 receptor subunit alpha |
| Uniprot ID | |
| 功能 | Receptor for IL10; binds IL10 with a high affinity. |
| 分子量 | Theoretical: 60 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |