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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IQSEC3 Polyclonal Antibody

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货号 TMAB-07784

Anti-IQSEC3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IQSEC3。Anti-IQSEC3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-IQSEC3 Polyclonal Antibody

Anti-IQSEC3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07784

Anti-IQSEC3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IQSEC3。Anti-IQSEC3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-IQSEC3 Polyclonal Antibody is a Rabbit antibody targeting IQSEC3. Anti-IQSEC3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Expressed specifically in the adult brain, predominantly in the cerebral cortex and the olfactory bulb, but not in the fetal brain. Expressed only in mature neurons, but not in undifferentiated neural stem precursor cells (NSPCs), nor in glioma cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景IQSEC3 (IQ motif and SEC7 domain-containing protein 3), also known as KIAA1110, is a 1,182 amino acid protein that belongs to the BRAG family. Localizing to the cytoplasm, IQSEC3 is expressed predominantly in adult brain, where it is observed predominantly in the cerebral cortex and olfactory bulb, with no expression found in the fetal brain. IQSEC3 contains an IQ domain, a PH domain and a SEC7 domain, and interacts with SAP 97 and PSD-95. Acting as a guanine nucleotide exchange factor (GEF) for ARF1, IQSEC3 is encoded by a gene that maps to human chromosome 12p13.33 and mouse chromosome 6 F1. Mutations to the gene encoding IQSEC2 have been linked to non-syndromic X-linked intellectual disability, while both IQSEC1 and IQSEC3 may be candidates for autosomal ID screening. IQSEC3 exists as two alternatively spliced isoforms.
抗原信息
免疫原
KLH conjugated synthetic peptide: human IQSEC3
抗原种属
Human
基因名称
IQSEC3
基因ID
440073
蛋白名称
IQ motif and SEC7 domain-containing protein 3
Uniprot ID
Q9UPP2
功能
Acts as a guanine nucleotide exchange factor (GEF) for ARF1.
化学信息
分子量Theoretical: 127 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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