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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-E2F5 Polyclonal Antibody

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货号 TMAB-05395

Anti-E2F5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 E2F5。Anti-E2F5 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-E2F5 Polyclonal Antibody

Anti-E2F5 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05395

Anti-E2F5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 E2F5。Anti-E2F5 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-E2F5 Polyclonal Antibody is a Rabbit antibody targeting E2F5. Anti-E2F5 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse)
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.
抗原信息
免疫原
KLH conjugated synthetic peptide: human E2F5
抗原种属
Human
基因名称
E2F5
基因ID
1875
蛋白名称
Transcription factor E2F5
Uniprot ID
Q15329
功能
Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation.
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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