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Anti-EpCAM/TROP1 Antibody (1A804)

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产品编号 TMAY-03372

Anti-EpCAM/TROP1 Antibody (1A804) 是一种 Rabbit 抗体,靶向 EpCAM/TROP1。Anti-EpCAM/TROP1 Antibody (1A804) 可用于 WB,ELISA,ELISA(Det),IHC-P。

Anti-EpCAM/TROP1 Antibody (1A804)

Anti-EpCAM/TROP1 Antibody (1A804)

Rating icon 还可以
产品编号 TMAY-03372

Anti-EpCAM/TROP1 Antibody (1A804) 是一种 Rabbit 抗体,靶向 EpCAM/TROP1。Anti-EpCAM/TROP1 Antibody (1A804) 可用于 WB,ELISA,ELISA(Det),IHC-P。

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产品介绍

生物活性
产品描述
Anti-EpCAM/TROP1 Antibody (1A804) is a Rabbit antibody targeting EpCAM/TROP1. Anti-EpCAM/TROP1 Antibody (1A804) can be used in WB,ELISA,ELISA(Det),IHC-P.
Ig Type
Monoclonal Rabbit IgG
克隆号
1A804
交叉反应
Mouse
验证活性
1. Immunochemical staining of mouse EpCAM in mouse uterus with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.

2. Immunochemical staining of mouse EpCAM in mouse stomach with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.

3. Immunochemical staining of mouse EpCAM in mouse intestine with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.

4. Anti-EPCAM rabbit monoclonal antibody at 1:500 dilution.

-Lane A: 293T Whole Cell lysate.

-Lysates/proteins at 30 μg per lane.

-Secondary

-Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

-Developed using the Odyssey technique.

-Performed under reducing conditions.

-Predicted band size:35 kDa.

-Observed band size:38 kDa
应用
WB,ELISA,ELISA(Det),IHC-P
推荐剂量
WB: 1:500-1:1000; ELISA: 1:25000-1:50000; IHC-P: 1:500-1:2000; ELISA(Det): 1:5000-1:50000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse EpCAM / TROP-1 / TACSTD1 (rM EpCAM / TROP-1 / TACSTD1; TMPY-01766; NP_032558.2; Met 1-Thr 266).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse EpCAM / TROP-1 / TACSTD1 protein (TMPY-01766)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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