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Anti-CD86 Antibody (5Q233)

货号 TMAB-04086 一键复制产品信息
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Anti-CD86 Antibody (5Q233) 是一种 Mouse 抗体，靶向 CD86。Anti-CD86 Antibody (5Q233) 可用于 WB。

Anti-CD86 Antibody (5Q233)

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货号 TMAB-04086

Anti-CD86 Antibody (5Q233) 是一种 Mouse 抗体，靶向 CD86。Anti-CD86 Antibody (5Q233) 可用于 WB。

Anti-CD86 Antibody (5Q233)
规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD86 Antibody (5Q233) is a Mouse antibody targeting CD86. Anti-CD86 Antibody (5Q233) can be used in WB.
Ig Type
IgG
克隆号
5Q233
反应种属
Human
验证活性
25 μg total protein per lane of various lysates (see on figure) probed with CD86 monoclonal antibody, unconjugated (TMAB-04086) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cell membrane; Single-pass type I membrane protein.
组织特异性Expressed by activated B-lymphocytes and monocytes.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
抗原信息
抗原种属
Human
基因名称
CD86
基因ID
942
蛋白名称
T-lymphocyte activation antigen CD86
Uniprot ID
P42081
功能
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
化学信息
分子量Theoretical: 37 kDa. Actual: 75 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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