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Anti-CD16/FCGR3 Antibody (3F748) 是一种 Rabbit 抗体,靶向 CD16/FCGR3。Anti-CD16/FCGR3 Antibody (3F748) 可用于 FCM。
Anti-CD16/FCGR3 Antibody (3F748) 是一种 Rabbit 抗体,靶向 CD16/FCGR3。Anti-CD16/FCGR3 Antibody (3F748) 可用于 FCM。
产品描述 | Anti-CD16/FCGR3 Antibody (3F748) is a Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody (3F748) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 3F748 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human CD16 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD16, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
应用 | FCM |
推荐剂量 | FCM: 1:25-1:100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD16a/Fc gamma RIIIa (rh CD16a/Fc gamma RIIIa; TMPY-00763; P08637-1; Met1-Gln208,176F). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes. |
偶联 | Unconjugated |
其他可选修饰符 | FITC |
可提供抗体种类 | 2 |
免疫原 | Recombinant Human CD16a/Fc gamma RIIIa Protein (TMPY-00763) |
抗原种属 | Human |
研究领域 | Fc Receptors |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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