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Anti-REG3G Antibody (5Q173) 是一种 Rabbit 抗体,靶向 REG3G。Anti-REG3G Antibody (5Q173) 可用于 ELISA。
Anti-REG3G Antibody (5Q173) 是一种 Rabbit 抗体,靶向 REG3G。Anti-REG3G Antibody (5Q173) 可用于 ELISA。
产品描述 | Anti-REG3G Antibody (5Q173) is a Rabbit antibody targeting REG3G. Anti-REG3G Antibody (5Q173) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 5Q173 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human REG3G (rh REG3G; TMPY-01406; NP_001008388.1; Met 1-Asp 175). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family, which consists of four subtypes (types I, II, III, IV) based on the primary structures of the encoded proteins of the genes, which are associated with tissue repair and have been directly implicated in pancreatic beta-cell regeneration. Reg proteins are expressed in various organs and are involved in cancers and neurodegenerative diseases. They display a typical C-type lectin-like domain but possess additional highly conserved amino acids. Regenerating islet-derived 3 gamma (REG3G), also known as pancreatitis-associated protein 1B (PAP1B), is a member of the secreted Reg superfamily and contains one typical C-type lectin domain. REG3G is expressed weakly in pancreas, strongly in intestinal tract, but not in hyperplastic islets REG3G might be a stress protein involved in the control of bacterial proliferation. It was indicated that REG3G specifically targets Gram-positive bacteria because it binds to their surface peptidoglycan layer, and serves as one of several antimicrobial peptides produced by paneth cells via stimulation of toll-like receptors (TLRs) by pathogen-associated molecular patterns (PAMPs). |
偶联 | Unconjugated |
免疫原 | Recombinant Human REG3G protein (TMPY-01406) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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