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别名 Sentrin-Specific Protease 8, Sentrin/SUMO-Specific Protease SENP8, SENP8, PRSC2, Protease Cysteine 2, NEDP1, NEDD8-Specific Protease 1, Deneddylase-1, DEN1
Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.


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Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 148 | 2-4周 | |
| 10 μg | ¥ 220 | 2-4周 | |
| 20 μg | ¥ 318 | 2-4周 | |
| 50 μg | ¥ 540 | 2-4周 | |
| 100 μg | ¥ 783 | 2-4周 | |
| 200 μg | ¥ 1,150 | 2-4周 | |
| 500 μg | ¥ 1,930 | 2-4周 | |
| 1 mg | ¥ 2,760 | 2-4周 |
| 产品描述 | Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins. |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | N-6xHis |
| 蛋白编号 | Q96LD8 |
| 氨基酸序列 | Met1-Lys212 |
| 蛋白构建 | Met1-Lys212 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| 缓冲液 | Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4. |
| 别名 | Sentrin-Specific Protease 8, Sentrin/SUMO-Specific Protease SENP8, SENP8, PRSC2, Protease Cysteine 2, NEDP1, NEDD8-Specific Protease 1, Deneddylase-1, DEN1 |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 22 KDa (reducing condition) |
| 运输方式 | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| 存储 |
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