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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FZD3 Polyclonal Antibody

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货号 TMAB-06227

Anti-FZD3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FZD3。Anti-FZD3 Polyclonal Antibody 可用于 WB,ELISA。

Anti-FZD3 Polyclonal Antibody

Anti-FZD3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06227

Anti-FZD3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FZD3。Anti-FZD3 Polyclonal Antibody 可用于 WB,ELISA。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
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产品介绍

生物活性
产品描述
Anti-FZD3 Polyclonal Antibody is a Rabbit antibody targeting FZD3. Anti-FZD3 Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
反应种属
Human,Rat
应用WBELISA
推荐剂量
WB: 1:500-1000; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
组织特异性Widely expressed. Relatively high expression in the CNS, including regions of the limbic system, in kidney, pancreas, skeletal muscle, uterus and testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010]
抗原信息
免疫原
Recombinant Protein: human FZD3 protein
抗原种属
Human
基因名称
FZD3
基因ID
7976
蛋白名称
Frizzled-3
Uniprot ID
Q9NPG1
功能
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
化学信息
分子量Theoretical: 74 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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