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Anti-Coagulation factor VII/F7 Antibody-HRP (5U957)
还可以产品编号 TMAY-03048H
Anti-Coagulation factor VII/F7 Antibody-HRP (5U957) 是一种 HRP-conjugated Rabbit 抗体，靶向 Coagulation factor VII/F7。Anti-Coagulation factor VII/F7 Antibody-HRP (5U957) 可用于 ELISA。
Anti-Coagulation factor VII/F7 Antibody-HRP (5U957)
Anti-Coagulation factor VII/F7 Antibody-HRP (5U957)
还可以产品编号 TMAY-03048H
Anti-Coagulation factor VII/F7 Antibody-HRP (5U957) 是一种 HRP-conjugated Rabbit 抗体，靶向 Coagulation factor VII/F7。Anti-Coagulation factor VII/F7 Antibody-HRP (5U957) 可用于 ELISA。
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| 产品描述 | Anti-Coagulation factor VII/F7 Antibody-HRP (5U957) is a HRP-conjugated Rabbit antibody targeting Coagulation factor VII/F7. Anti-Coagulation factor VII/F7 Antibody-HRP (5U957) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5U957 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 0.1-1 μg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse FVII (rM FVII; NP_034302.2Met 1-Leu 446), and conjugated with horseradish-peroxidase (HRP). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is an enzyme of the serine protease class, and Factor VII (FVII) deficiency is the most frequent among rare congenital bleeding disorders. Factor VII contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one peptidase S1 domain. The main role of factor VII is to initiate the process of coagulation in conjunction with tissue factor (TF). Tissue factor is found on the outside of blood vessels, normally not exposed to the blood stream. The action of the Factor VII is impeded by tissue factor pathway inhibitor (TFPI), which is released almost immediately after initiation of coagulation. Factor VII is vitamin K dependent and is produced in the liver. Upon vessel injury, tissue factor is exposed to the blood and circulating Factor VII. Once bound to TF, FVII is activated to FVIIa by different proteases, among which are thrombin (factor IIa), factor Xa, IXa, XIIa, and the FVIIa-TF complex itself. Recombinant activated factor VII (rFVIIa) is a haemostatic agent, which was originally developed for the treatment of haemophilia patients with inhibitors against factor FVIII or FIX. FVIIa binds specifically to endothelial protein C receptor (EPCR), a known cellular receptor for protein C and activated protein C, on the endothelium. rFVIIa is a novel hemostatic agent, originally developed for the treatment of hemorrhage in hemophiliacs with inhibitors, which has been successfully used recently in an increasing number of nonhemophilic bleeding conditions. |
| 偶联 | HRP |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Mouse FVII protein |
| 抗原种属 | Mouse |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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