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IL-37 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is Q9NZH6-2.

| 规格 | 价格 | 库存 | 数量 |
|---|
| 生物活性 | Human IL-18BP, hFc Tag captured on CM5 Chip via Protein A can bind Human IL-37, No Tag with an affinity constant of 0.12 μM as determined in SPR assay (Biacore T200). |
| 产品描述 | IL-37 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is Q9NZH6-2. |
| 种属 | Human |
| 表达系统 | E. coli |
| 蛋白编号 | Q9NZH6-2 |
| 别名 | 白介素,interleukin 37,IL-37,IL37,IL-1RP1,IL1RP1,IL-1H4,IL1H4,IL-1H,IL-1F7,IL1F7,FIL1Z,FIL1(ζ),FIL1(ZETA),FIL1 |
| 蛋白构建 | Lys27-Asp192 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 分子量 | 18.55 kDa (Predicted and reducing conditions) |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from 0.22 μm filtered solution in 20 mM PBS, 2 mM DTT (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | IL-37 is a unique member of the IL-1 family of cytokines, which functions as a natural suppressor of inflammatory and immune responses. Immune and non-immune cells produce IL-37 precursor following pro-inflammatory stimuli. Following activating cleavage by caspase-1, mature IL-37 translocates to the nucleus, where it suppresses transcription of pro-inflammatory genes. |