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Anti-AHR Antibody (8Z303)
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产品编号 TMAC-00277
别名 Class E basic helix-loop-helix protein 76 (bHLHe76), bHLHe76, Aryl hydrocarbon receptor, AHR, Ah receptor
Anti-AHR Antibody (8Z303) 是一种 Rabbit 抗体，靶向 AHR。Anti-AHR Antibody (8Z303) 可用于 WB,ICC/IF。
Anti-AHR Antibody (8Z303)
Anti-AHR Antibody (8Z303)
还可以产品编号 TMAC-00277 别名 Class E basic helix-loop-helix protein 76 (bHLHe76), bHLHe76, Aryl hydrocarbon receptor, AHR, Ah receptor
Anti-AHR Antibody (8Z303) 是一种 Rabbit 抗体，靶向 AHR。Anti-AHR Antibody (8Z303) 可用于 WB,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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| 产品描述 | Anti-AHR Antibody (8Z303) is a Rabbit antibody targeting AHR. Anti-AHR Antibody (8Z303) can be used in WB,ICC/IF. |
| 别名 | Class E basic helix-loop-helix protein 76 (bHLHe76), bHLHe76, Aryl hydrocarbon receptor, AHR, Ah receptor |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of AhR on human lung lysates using anti-AhR antibody at 1/1,000 dilution. 2. ICC staining AhR in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining AhR in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining AhR in NIH/3T3 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; ICC/IF: 1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is the prototype for a family of toxic halogenated aromatic compounds that are thought to cause adverse reproductive, immunologic and metabolic effects. Many biological responses to TCDD are mediated through ligand binding to the aromatic hydrocarbon (Ah) receptor, also known as AhR. Ah Receptor is a ligand dependent transcription factor that interacts with specific DNA sequences, termed xenobiotic responsive elements (XREs), and that lies upstream of TCDD-inducible genes. Upon binding to the ligand, Ah Receptor binds to the Ah Receptor nuclear translocator (Arnt), and the complex is translocated from the cytoplasm to the nucleus. Arnt is required for Ah R eceptor to bind to XRE. Ah Receptor and Arnt are members of a family of transcription factors that contain a basic helix-loop-helix motif and a common "PAS" motif. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 96 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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