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IFNAR1 Protein, Rhesus macaque, Recombinant (His)

Synonyms: 干扰素, β-type antiviral protein, α-type antiviral protein, IFN-α/β receptor 1, IFN-α/β R1, IFN-alpha/beta receptor 1, IFN-alpha/beta R1, IFN-al, human interferon-α receptor (HuIFN-α-Rec)10IFRC, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, Cytokine receptor family 2 member 1, Cytokine receptor class-II member 1, CRF2-1, beta-type antiviral protein, AVP, alpha-type antiviral protein
货号 TMPJ-00331 一键复制产品信息
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Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

IFNAR1 Protein, Rhesus macaque, Recombinant (His)

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货号 TMPJ-00331

别名 干扰素, β-type antiviral protein, α-type antiviral protein, IFN-α/β receptor 1, IFN-α/β R1, IFN-alpha/beta receptor 1, IFN-alpha/beta R1, IFN-al, human interferon-α receptor (HuIFN-α-Rec)10IFRC, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, Cytokine receptor family 2 member 1, Cytokine receptor class-II member 1, CRF2-1, beta-type antiviral protein, AVP, alpha-type antiviral protein

Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

IFNAR1 Protein, Rhesus macaque, Recombinant (His)
其他形式的 “IFNAR1 Protein, Rhesus macaque, Recombinant (His)”:
规格价格库存数量
5 μg
¥ 492
35日内发货
10 μg
¥ 820
35日内发货
20 μg
¥ 1,290
35日内发货
50 μg
¥ 2,480
35日内发货
100 μg
¥ 3,980
35日内发货
200 μg
¥ 6,420
35日内发货
500 μg
¥ 12,100
35日内发货
1 mg
¥ 17,300
35日内发货
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产品介绍


生物活性
产品描述
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
种属
Rhesus
表达系统
HEK293 Cells
标签
C-6xHis
蛋白编号A0A7N9D7J0
氨基酸序列
Ala25-Lys437
蛋白构建
Ala25-Lys437
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液
Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名
干扰素, β-type antiviral protein, α-type antiviral protein, IFN-α/β receptor 1, IFN-α/β R1, IFN-alpha/beta receptor 1, IFN-alpha/beta R1, IFN-al, human interferon-α receptor (HuIFN-α-Rec)10IFRC, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, Cytokine receptor family 2 member 1, Cytokine receptor class-II member 1, CRF2-1, beta-type antiviral protein, AVP, alpha-type antiviral protein
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量70-120 KDa (reducing condition)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

对于不同动物的给药剂量换算,您也可以参考 更多

技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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