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Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) 是一种抗体,靶向 TRAIL R2/DR5/TNFRSF10B。Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) 可用于 ELISA, WB, IF。
Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) 是一种抗体,靶向 TRAIL R2/DR5/TNFRSF10B。Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) 可用于 ELISA, WB, IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,310 | 5日内发货 | |
100 μL | ¥ 2,180 | 5日内发货 |
产品描述 | Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) is an antibody targeting TRAIL R2/DR5/TNFRSF10B. Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) can be used in ELISA, WB, IF. |
别名 | ZTNFR9, TRICKB, TRICK2A, TRICK2, TRAILR2, TRAIL receptor 2, TRAIL R2, TNFRSF10B, KILLER/DR5, KILLER, Fas-like protein, DR5TRICK2B, DR5, CD262 |
Ig Type | hIgG1 |
克隆号 | 2E303 |
交叉反应 | Human |
验证活性 | 1. Western Blot -Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, U251 whole cell lysate -All lanes: TNFRSF10B antibody at 1:500 -Secondary: Goat polyclonal to Human IgG at 1/50000 dilution -Predicted band size: 13 kDa -Observed band size: 13 kDa 2. Immunofluorescence staining of Hela cell with TMAH-01187 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Human IgG(H+L). |
应用 | ELISA, WB, IF |
推荐剂量 | WB:1:500-1:2000; IF:1:50-1:200. |
抗体种类 | Monoclonal |
亚细胞定位 | Membrane; Single-pass type I membrane protein. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
研究背景 | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: Human TNFRSF10B Protein |
抗原种属 | Human |
基因ID | 8795 |
Uniprot ID | |
研究领域 | Cancer, Cardiovascular, Cell biology, Signal transduction |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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