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别名 ZTNFR9, TRICKB, TRICK2A, TRICK2, TRAILR2, TRAIL receptor 2, TRAIL R2, TNFRSF10B, KILLER/DR5, KILLER, Fas-like protein, DR5TRICK2B, DR5, CD262
Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) 是一种抗体,靶向 TRAIL R2/DR5/TNFRSF10B。Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) 可用于 ELISA,IF,WB。
Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) 是一种抗体,靶向 TRAIL R2/DR5/TNFRSF10B。Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) 可用于 ELISA,IF,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
| 产品描述 | Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) is an antibody targeting TRAIL R2/DR5/TNFRSF10B. Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) can be used in ELISA,IF,WB. |
| 别名 | ZTNFR9, TRICKB, TRICK2A, TRICK2, TRAILR2, TRAIL receptor 2, TRAIL R2, TNFRSF10B, KILLER/DR5, KILLER, Fas-like protein, DR5TRICK2B, DR5, CD262 |
| Ig Type | hIgG1 |
| 克隆号 | 2E303 |
| 交叉反应 | Human |
| 验证活性 | 1. Western Blot -Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, U251 whole cell lysate -All lanes: TNFRSF10B antibody at 1:500 -Secondary: Goat polyclonal to Human IgG at 1/50000 dilution -Predicted band size: 13 kDa -Observed band size: 13 kDa 2. Immunofluorescence staining of Hela cell with TMAH-01187 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Human IgG(H+L). |
| 应用 | ELISAIFWB |
| 推荐剂量 | WB:1:500-1:2000; IF:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines such as HeLaS3, K-562, HL-60, SW480, A-549 and G-361; highly expressed in heart, peripheral blood lymphocytes, liver, pancreas, spleen, thymus, prostate, ovary, uterus, |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human TNFRSF10B Protein |
| 抗原种属 | Human |
| 基因名称 | TNFRSF10B |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Cancer, Cardiovascular, Cell biology, Signal transduction |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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