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IFN-omega Protein, Human, Recombinant (hFc)

产品编号 TMPY-00833

别名: 干扰素, IFNW1, IFN-ω 1, interferon ω-1, IFN-omega 1, IFN-ω, interferon, omega 1, interferon, ω 1, interferon omega-1

IFN-omega Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.6 kDa and the accession number is A0A7R8GUW6.

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IFN-omega Protein, Human, Recombinant (hFc)

规格	价格/CNY		货期	数量
100 μg	￥ 2,940		5日内发货

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参考文献

生物活性	Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitis virus (VSV). The EC50 for this effect is 0.03-0.3 ng/mL.
产品描述	IFN-omega Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.6 kDa and the accession number is A0A7R8GUW6.

种属	Human
表达系统	HEK293 Cells
标签	N-hFc
蛋白编号	A0A7R8GUW6
别名	干扰素, IFNW1, IFN-ω 1, interferon ω-1, IFN-omega 1, IFN-ω, interferon, omega 1, interferon, ω 1, interferon omega-1
蛋白构建	The Human IFNω (NP_002168.1) (Cys 24-Ser 195) was fused with the Fc region of Human IgG1 at the N-terminus.
蛋白纯度	> 92 % as determined by SDS-PAGE
分子量	46.6 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	IFNs are a large family of proteins having antiviral, antiproliferative, and immunomodulatory effects, and are divided into two major classes, type I and type II, based on differences in receptor binding and nucleotide sequence. Type I IFNs consist of IFN α, β, τ, and ω and bind to the type I IFN receptor, whereas IFN-γ is the only type II IFN and is specific for the type II IFN receptor. Human IFN-ω, was identified by three independent groups in 1985 and is structurally related to IFN-α and -β. Both human IFN-ω and IFN-α are produced by virally induced leukocytes and have similar antiviral activities on human cell lines, and a sizeable proportion (at least 1%) of the total antiviral activity of leukocyte IFN is contributed by IFN-ωl. Also, it was reported that IFN-ω could inhibit the growth of human tumors in vivo.

参考文献

1. Capon D.J., et al.,(1985), Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides. Mol. Cell. Biol. 5:768-779. 2. Adolf G.R., et al., (1991), Human interferon omega 1: isolation of the gene, expression in Chinese hamster ovary cells and characterization of the recombinant protein.Biochim. Biophys. Acta 1089:167-174. 3. Humphray S.J., et al.,(2004), DNA sequence and analysis of human chromosome 9.Nature 429:369-374.

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Keywords

IFN-omega Protein, Human, Recombinant (hFc) IFN-w 1 干扰素 IFNW1 IFN-ω 1 interferon ω-1 interferon, w 1 IFN-omega 1 IFN-ω interferon, omega 1 interferon, ω 1 IFNW-1 IFNW 1 interferon w-1 interferon omega-1 recombinant recombinant-proteins proteins protein

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