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DLL4 Protein, Human, Recombinant (hFc) V2
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货号 TMPY-00776U
别名 δ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosophila), Delta-like 4
DLL4 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q9NR61.
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DLL4 Protein, Human, Recombinant (hFc) V2
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPY-00776U 别名 δ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosophila), Delta-like 4
DLL4 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q9NR61.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 429 | 6-8日内发货 | |
| 10 μg | ¥ 695 | 6-8日内发货 | |
| 20 μg | ¥ 1,130 | 5日内发货 | |
| 50 μg | ¥ 2,260 | 5日内发货 | |
| 100 μg | ¥ 4,010 | 5日内发货 | |
| 200 μg | ¥ 7,090 | 5日内发货 | |
| 500 μg | ¥ 15,000 | 5日内发货 |
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| 产品描述 | DLL4 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q9NR61. |
| 生物活性 | Immobilized Human DLL4, hFc Tag at 1 μg/ml (100 μl/Well) on the plate. Dose response curve for Biotinylated Anti-DLL4 Antibody, hFc Tag with the EC50 of 16.5 ng/ml determined by ELISA (QC Test). Human DLL4, hFc Tag captured on CM5 Chip via Protein A can bind Human Notch 1, His Tag with an affinity constant of 0.48 μM as determined in SPR assay (Biacore T200). |
| 研究背景 | Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-hFc |
| 蛋白编号 | Q9NR61 |
| 蛋白构建 | Ser27-Pro524 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | δ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosophila), Delta-like 4 |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 81.1 kDa (Predicted); 82-90 kDa (Due to glycosylation) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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