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Anti-CD166/ALCAM Antibody (5K951)
还可以产品编号 TMAY-03906
Anti-CD166/ALCAM Antibody (5K951) 是一种 Rabbit 抗体，靶向 CD166/ALCAM。Anti-CD166/ALCAM Antibody (5K951) 可用于 ELISA,FCM。
Anti-CD166/ALCAM Antibody (5K951)
Anti-CD166/ALCAM Antibody (5K951)
还可以产品编号 TMAY-03906
Anti-CD166/ALCAM Antibody (5K951) 是一种 Rabbit 抗体，靶向 CD166/ALCAM。Anti-CD166/ALCAM Antibody (5K951) 可用于 ELISA,FCM。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-CD166/ALCAM Antibody (5K951) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5K951) can be used in ELISA,FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5K951 |
| 交叉反应 | Cynomolgus |
| 验证活性 | Flow cytometric analysis of Cynomolgus CD166 expression on Cynomolgus monocytes. Cells were stained with purified anti-CD166, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| 应用 | ELISA,FCM |
| 推荐剂量 | ELISA: 1:5000-1:10000; FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Cynomolgus CD166/ALCAM ( TMPY-03520; G7NZQ8; Met1-Ala526). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | FITC/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Cynomolgus CD166/ALCAM Protein (TMPY-03520) |
| 抗原种属 | Cynomolgus |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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