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顶部生物活性储存和溶解信息计算器

Anti-CD166/ALCAM Antibody (5K951)

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产品编号 TMAY-03906
别名 MEMD, CD166, activated leukocyte cell adhesion molecule

Anti-CD166/ALCAM Antibody (5K951) 是一种 Rabbit 抗体，靶向 CD166/ALCAM。Anti-CD166/ALCAM Antibody (5K951) 可用于 ELISA,FCM。

Anti-CD166/ALCAM Antibody (5K951)

Anti-CD166/ALCAM Antibody (5K951)

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产品编号 TMAY-03906 别名 MEMD, CD166, activated leukocyte cell adhesion molecule

Anti-CD166/ALCAM Antibody (5K951) 是一种 Rabbit 抗体，靶向 CD166/ALCAM。Anti-CD166/ALCAM Antibody (5K951) 可用于 ELISA,FCM。

规格价格库存数量
100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD166/ALCAM Antibody (5K951) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5K951) can be used in ELISA,FCM.
别名MEMD, CD166, activated leukocyte cell adhesion molecule
Ig Type
Rabbit IgG
克隆号
5K951
交叉反应
Cynomolgus
特异性
Cynomolgus CD166/ALCAM
验证活性
Flow cytometric analysis of Cynomolgus CD166 expression on Cynomolgus monocytes. Cells were stained with purified anti-CD166, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
应用ELISAFCM
推荐剂量
ELISA: 1:5000-1:10000; FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Cynomolgus CD166/ALCAM ( TMPY-03520; G7NZQ8; Met1-Ala526).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
FITC/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Cynomolgus CD166/ALCAM Protein (TMPY-03520)
抗原种属
Cynomolgus
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

CD-166CD 166

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4个月前
5.0
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