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Anti-Phospho-A Raf (Tyr301+Tyr302) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-A Raf (Tyr301+Tyr302)。Anti-Phospho-A Raf (Tyr301+Tyr302) Polyclonal Antibody 可用于 WB。
Anti-Phospho-A Raf (Tyr301+Tyr302) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-A Raf (Tyr301+Tyr302)。Anti-Phospho-A Raf (Tyr301+Tyr302) Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-Phospho-A Raf (Tyr301+Tyr302) Polyclonal Antibody is a Rabbit antibody targeting Phospho-A Raf (Tyr301+Tyr302). Anti-Phospho-A Raf (Tyr301+Tyr302) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 组织特异性 | Predominantly in urogenital tissues. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human A Raf around the phosphorylation site of Tyr301/302 |
| 抗原种属 | Human |
| 基因名称 | ARAF |
| 基因ID | |
| 蛋白名称 | Serine/threonine-protein kinase A-Raf |
| Uniprot ID | |
| 功能 | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. |
| 分子量 | Theoretical: 67 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |