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Anti-MAGEA1 Antibody (7O578)

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货号 TMAB-08513

Anti-MAGEA1 Antibody (7O578) 是一种 Rabbit 抗体，靶向 MAGEA1。Anti-MAGEA1 Antibody (7O578) 可用于 FCM。

Anti-MAGEA1 Antibody (7O578)

Anti-MAGEA1 Antibody (7O578)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08513

Anti-MAGEA1 Antibody (7O578) 是一种 Rabbit 抗体，靶向 MAGEA1。Anti-MAGEA1 Antibody (7O578) 可用于 FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-MAGEA1 Antibody (7O578) is a Rabbit antibody targeting MAGEA1. Anti-MAGEA1 Antibody (7O578) can be used in FCM.
Ig Type
IgG
克隆号
7O578
反应种属
Human
应用FCM
推荐剂量
FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The MAGE 1 gene is a member of the melanoma antigen encoding gene family. These genes encode for HLA-restricted tumor associated rejection antigens recognized by cytotoxic T lymphocytes. Some of these target antigens may be potentially useful for cancer specific immunotherapy. The expression of MAGE genes has been reported not only in melanoma but also in various other malignant tumors such as hepatocellular carcinoma and germ cell tumors.
抗原信息
基因名称
MAGEA1
基因ID
4100
蛋白名称
Melanoma-associated antigen 1
功能
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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