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Anti-NLRP3 Polyclonal Antibody 5

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Anti-NLRP3 Polyclonal Antibody 5
产品编号 TMAB-01247

Anti-NLRP3 Polyclonal Antibody 5 是一种 Rabbit 抗体,靶向 NLRP3。Anti-NLRP3 Polyclonal Antibody 5 可用于 WB。

Anti-NLRP3 Polyclonal Antibody 5

Anti-NLRP3 Polyclonal Antibody 5

Rating icon 还可以
Anti-NLRP3 Polyclonal Antibody 5
产品编号 TMAB-01247

Anti-NLRP3 Polyclonal Antibody 5 是一种 Rabbit 抗体,靶向 NLRP3。Anti-NLRP3 Polyclonal Antibody 5 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
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100 μL
¥ 1,975
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200 μL
¥ 2,795
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产品介绍

生物活性
产品描述
Anti-NLRP3 Polyclonal Antibody 5 is a Rabbit antibody targeting NLRP3. Anti-NLRP3 Polyclonal Antibody 5 can be used in WB.
Ig Type
IgG
交叉反应
Human
验证活性
THP-1 (H) cells were treated with or without LPS (10 µg/ml) for 8 h, 25 μg total protein per Lane of cell lysates probed with NLRP3 polyclonal antibody, unconjugated (TMAB-01247) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
应用
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm.
抗原信息
免疫原
Recombinant Protein: human NLRP3
抗原种属
Human
基因ID
Uniprot ID
研究领域
TNF,Inflammatory mediators,Macrophage / Inflamm.,NFkB Pathway
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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