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Anti-Transferrin Receptor/TFRC Antibody (4M349)
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产品编号 TMAC-04109
别名 Transferrin receptor protein 1, T9, p90
Anti-Transferrin Receptor/TFRC Antibody (4M349) 是一种 Rabbit 抗体，靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody (4M349) 可用于 WB,IHC,IP,FCM。
Anti-Transferrin Receptor/TFRC Antibody (4M349)
Anti-Transferrin Receptor/TFRC Antibody (4M349)
还可以产品编号 TMAC-04109 别名 Transferrin receptor protein 1, T9, p90
Anti-Transferrin Receptor/TFRC Antibody (4M349) 是一种 Rabbit 抗体，靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody (4M349) 可用于 WB,IHC,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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抗原信息
化学信息
| 产品描述 | Anti-Transferrin Receptor/TFRC Antibody (4M349) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (4M349) can be used in WB,IHC,IP,FCM. |
| 别名 | Transferrin receptor protein 1, T9, p90 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of Transferrin Receptor on mouse placenta lysates using anti-Transferrin Receptor antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Transferrin Receptor antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Transferrin Receptor antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Transferrin Receptor antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-Transferrin Receptor antibody. Counter stained with hematoxylin. 6. Flow cytometric analysis of Hela cells with Transferrin Receptor antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | CD71, also known as the transferrin receptor (TFR), is a type II membrane glycoprotein that exists as a disulfide-linked homodimer of two identical subunits. CD71 binds to two molecules of transferrin and a serum iron-transport protein, and directs the cellular uptake of iron via receptor-mediated endocytosis. CD71 is expressed, typically at high levels, on all proliferating cells, reticulocytes and erythroid precursors. It is not expressed on resting leukocytes, but is upregulated upon activation of lymphocytes, monocytes and macrophages. CD71 is also found on most dividing cells and on brain endothelium. A second transferrin receptor, TFR2, also mediates the uptake of transferrin-bound iron. TFR2 is a two-subunit homodimer and is highly expressed in liver as well as in hepatocytes and erythroid precursors. Mutations in the TFR2 gene result in hereditary hemochromatosis type III (HFE3), an iron overloading disorder predominant in Caucasians. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 85 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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