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Anti-RNF105 Polyclonal Antibody

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货号 TMAB-12279

Anti-RNF105 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RNF105。Anti-RNF105 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-RNF105 Polyclonal Antibody

Anti-RNF105 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12279

Anti-RNF105 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RNF105。Anti-RNF105 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-RNF105 Polyclonal Antibody is a Rabbit antibody targeting RNF105. Anti-RNF105 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Found in all tissues examined.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RNF105
抗原种属
Human
基因名称
TTC3
基因ID
蛋白名称
E3 ubiquitin-protein ligase TTC3
Uniprot ID
功能
E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
化学信息
分子量Theoretical: 230 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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