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顶部生物活性储存和溶解信息计算器

Anti-PARP1 Antibody (6J247)

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Anti-PARP1 Antibody (6J247)
产品编号 TMAC-00892
别名 PPOL, Poly-PARP, PARS, PARP-1, PARP, pADPRT-1, ARTD1, ADPRT1, ADPRT 1, ADPRT

Anti-PARP1 Antibody (6J247) 是一种 Mouse 抗体，靶向 PARP1。Anti-PARP1 Antibody (6J247) 可用于 WB。

Anti-PARP1 Antibody (6J247)

Anti-PARP1 Antibody (6J247)

Rating icon 还可以
Anti-PARP1 Antibody (6J247)
产品编号 TMAC-00892 别名 PPOL, Poly-PARP, PARS, PARP-1, PARP, pADPRT-1, ARTD1, ADPRT1, ADPRT 1, ADPRT

Anti-PARP1 Antibody (6J247) 是一种 Mouse 抗体，靶向 PARP1。Anti-PARP1 Antibody (6J247) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,345
5日内发货
100 μL
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-PARP1 Antibody (6J247) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (6J247) can be used in WB.
别名PPOL, Poly-PARP, PARS, PARP-1, PARP, pADPRT-1, ARTD1, ADPRT1, ADPRT 1, ADPRT
交叉反应
Human
验证活性
1. Western blot analysis of 1) Jurkat ,2) Hela cells, using TMAC-00892 diluted at 1:2,000.
应用
WB
推荐剂量
WB: 1:1000-3000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Affinity purification using immunogen.
性状Liquid
缓冲液Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.
偶联与修饰
偶联
Unconjugated
抗原信息
Uniprot ID
P09874
化学信息
分子量Actual: 116, 89 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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