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Anti-PICK1 Antibody (5X729)
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产品编号 TMAC-03296
别名 Protein that interacts with C kinase 1, Protein kinase C-alpha-binding protein, Protein kinase C alpha binding protein, Protein interacting with PRKCA 1, Protein interacting with PRKCA, Protein interacting with C kinase 1, PRKCABP, PRKCA-binding protein, PRKCA binding protein, PICK1_HUMAN, Pick1, PICK 1, OTTHUMP00000028509, MGC15204, dJ1039K5
Anti-PICK1 Antibody (5X729) 是一种 Rabbit 抗体，靶向 PICK1。Anti-PICK1 Antibody (5X729) 可用于 WB,IP,FCM。
Anti-PICK1 Antibody (5X729)
Anti-PICK1 Antibody (5X729)
还可以产品编号 TMAC-03296 别名 Protein that interacts with C kinase 1, Protein kinase C-alpha-binding protein, Protein kinase C alpha binding protein, Protein interacting with PRKCA 1, Protein interacting with PRKCA, Protein interacting with C kinase 1, PRKCABP, PRKCA-binding protein, PRKCA binding protein, PICK1_HUMAN, Pick1, PICK 1, OTTHUMP00000028509, MGC15204, dJ1039K5
Anti-PICK1 Antibody (5X729) 是一种 Rabbit 抗体，靶向 PICK1。Anti-PICK1 Antibody (5X729) 可用于 WB,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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产品介绍
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抗原信息
化学信息
| 产品描述 | Anti-PICK1 Antibody (5X729) is a Rabbit antibody targeting PICK1. Anti-PICK1 Antibody (5X729) can be used in WB,IP,FCM. |
| 别名 | Protein that interacts with C kinase 1, Protein kinase C-alpha-binding protein, Protein kinase C alpha binding protein, Protein interacting with PRKCA 1, Protein interacting with PRKCA, Protein interacting with C kinase 1, PRKCABP, PRKCA-binding protein, PRKCA binding protein, PICK1_HUMAN, Pick1, PICK 1, OTTHUMP00000028509, MGC15204, dJ1039K5 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of PICK1 on SK-Br-3 cell lysate using anti-PICK1 antibody at 1/5,000 dilution. 2. Flow cytometric analysis of 293T cells with PICK1 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:2000-5000; IP: 1:10-50; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Protein interacting with C kinase 1 (PICK1) is a PDZ-domain containing protein that is located in the perinuclear region and is phosphorylated in response to PKCα activation. PKCα, which is essential for the regulation of proliferation and differentiation in numerous cell types, contains within its catalytic region a PDZ-binding domain that is absent from other PKC isoforms. Mutation of the PICK1 PDZ domain inhibits the binding of PICK1 to PKCα. PICK1 also interacts with the carboxy terminus of a-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor, a neurotransmitter receptor located at excitatory synapses, suggesting that PICK1 plays a role in the modulation of synaptic transmission by targeting and anchoring AMPA to specific synapses. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: within N-terminal human PICK1 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 47 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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