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别名 抗小鼠 ICOS 抗体 (7E.17G9), 7E.17G9
Anti-Mouse ICOS Antibody (7E.17G9) 是一种小鼠抗ICOS单克隆抗体。Anti-Mouse ICOS Antibody (7E.17G9) 可上调 ICOS 表达、增强 T 细胞功能,显著抑制树突状细胞(DC)的免疫调节作用,并打破移植耐受。可用于炎症疾病、癌症与异种移植(如肾炎、肿瘤)的研究。
Anti-Mouse ICOS Antibody (7E.17G9) 是一种小鼠抗ICOS单克隆抗体。Anti-Mouse ICOS Antibody (7E.17G9) 可上调 ICOS 表达、增强 T 细胞功能,显著抑制树突状细胞(DC)的免疫调节作用,并打破移植耐受。可用于炎症疾病、癌症与异种移植(如肾炎、肿瘤)的研究。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 1,650 | 待询 | |
| 5 mg | ¥ 3,970 | 待询 | |
| 10 mg | 待询 | 待询 |
| 产品描述 | Anti-Mouse ICOS Antibody (7E.17G9) is a mouse anti-ICOS IgG2b monoclonal antibody.Anti-Mouse ICOS Antibody (7E.17G9) upregulates ICOS expression, enhances T cell function, significantly inhibits the immunomodulatory effect of dendritic cells (DCs), and breaks transplantation tolerance.It can be used in the research of inflammatory diseases, cancer and xenotransplantation, such as nephritis and tumors. |
| 体外活性 | Anti-Mouse ICOS Antibody (7E.17G9)(10 μg/mL,48 小时)可显著抑制 MPO/BAY 树突状细胞(DCs)诱导的 IL-10+ Tregs,并抑制 Tregs 活化 [2]。 |
| 体内活性 | Anti-Mouse ICOS Antibody (7E.17G9)(250–375 μg,腹腔注射,第 0、2、4、6 天)显著降低异位腹部心脏移植 PD-1 Tg B6 小鼠的移植耐受 [1]。 |
| 别名 | 抗小鼠 ICOS 抗体 (7E.17G9), 7E.17G9 |
| 克隆号 | 7E.17G9 |
| 反应种属 | Mouse |
| 应用 | ELISA FCM Functional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | Rat IgG2b kappa |
| 推荐同型对照 |
| 偶联 | Unconjugated |
| 基因ID | |
| Uniprot ID | |
| 靶点 | ICOS |
| 分子量 | 150 kDa |
| 存储 |
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