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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Brain2 Polyclonal Antibody

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货号 TMAB-03203

Anti-Brain2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Brain2。Anti-Brain2 Polyclonal Antibody 可用于 WB,FCM。

Anti-Brain2 Polyclonal Antibody

Anti-Brain2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03203

Anti-Brain2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Brain2。Anti-Brain2 Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Brain2 Polyclonal Antibody is a Rabbit antibody targeting Brain2. Anti-Brain2 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Cow,Horse,Rabbit)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed specifically in the neuroectodermal cell lineage.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. Brn-1 and Brn-2 are class III POU domain proteins. Expressed during the development of the forebrain and coexpressed in most layer II-V cortical neurons, Brn-1 and Brn-2 appear to critically control the initiation of radial migration of cortical neurons. Brn-2 is thought to be involved in smooth muscle cell development and differentiation. Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. Brn-3a has two functional transactivating domains, one at the amino terminus and one at the carboxy terminus. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Brain2/POU3F2
抗原种属
Human
基因名称
POU3F2
基因ID
5454
蛋白名称
POU domain, class 3, transcription factor 2
Uniprot ID
P20265
功能
Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters.
化学信息
分子量Theoretical: 49 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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