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LAMP1 Protein, Human, Recombinant (hFc)

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货号 TMPJ-00264

别名 Lysosome-Associated Membrane Protein 1, Lysosome-Associated Membrane Glycoprotein 1, LAMP-1, LAMP1, CD107a, CD107 Antigen-Like Family Member A

Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.

LAMP1 Protein, Human, Recombinant (hFc)
其他形式的 “LAMP1 Protein, Human, Recombinant (hFc)”:
LAMP1 Protein, Mouse, Recombinant (His)
LAMP1 Protein, Human, Recombinant (His)
LAMP1 Protein, Rat, Recombinant (hFc)

LAMP1 Protein, Human, Recombinant (hFc)

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPJ-00264 别名 Lysosome-Associated Membrane Protein 1, Lysosome-Associated Membrane Glycoprotein 1, LAMP-1, LAMP1, CD107a, CD107 Antigen-Like Family Member A

Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.

规格价格库存数量
5 μg
¥ 456
6-8日内发货
10 μg
¥ 740
6-8日内发货
20 μg
¥ 1,120
2-4周
50 μg
¥ 1,970
2-4周
100 μg
¥ 3,380
2-4周
200 μg
¥ 5,850
2-4周
500 μg
¥ 12,100
2-4周
1 mg
¥ 17,300
2-4周
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产品介绍

生物活性
产品描述
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
种属
Human
表达系统
HEK293 Cells
标签C-hFc
蛋白编号P11279
氨基酸序列Ala29-Met382
蛋白构建Ala29-Met382
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名Lysosome-Associated Membrane Protein 1, Lysosome-Associated Membrane Glycoprotein 1, LAMP-1, LAMP1, CD107a, CD107 Antigen-Like Family Member A
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量90-130 KDa (reducing condition)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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关键词

LAMP 1
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