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Anti-SPARCL1 Antibody-PE (7L739) 是一种 PE-conjugated Rabbit 抗体,靶向 SPARCL1。Anti-SPARCL1 Antibody-PE (7L739) 可用于 FCM。
Anti-SPARCL1 Antibody-PE (7L739) 是一种 PE-conjugated Rabbit 抗体,靶向 SPARCL1。Anti-SPARCL1 Antibody-PE (7L739) 可用于 FCM。
产品描述 | Anti-SPARCL1 Antibody-PE (7L739) is a PE-conjugated Rabbit antibody targeting SPARCL1. Anti-SPARCL1 Antibody-PE (7L739) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 7L739 |
交叉反应 | Human |
验证活性 | Profile of anti-SPARCL1 reactivity on HL60 cells analyzed by flow cytometry. |
应用 | FCM |
推荐剂量 | 5 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human SPARCL1 (rh SPARCL1; NP_004675.3Met 1-Phe 664) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
研究背景 | SPARC-like protein 1 (SPARCL1; also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins. It contains three conserved structural domains that are implicated in the regulation of cell adhesion, migration, and proliferation. SPARCL1 is expressed during embryogenesis and tissue remodeling and is especially prominent in brain and vasculature. Its down-regulation in a number of cancers and the possibility of its functional compensation by SPARC has led to recent interest in hevin as a tumor suppressor and regulator of angiogenesis. SPARCL1 has antiadhesive properties, and loss of SPARCL1 expression is associated with increased proliferative activity and cell cycle progression. It is suggested that it may influence multiple cellular processes during distinct stages of brain development and function. Besides, SPARCL1 can influence the function of astroglial cells in the developing and mature central nervous system (CNS). |
偶联 | PE |
其他可选修饰符 | Unconjugated/FITC |
可提供抗体种类 | 3 |
免疫原 | Recombinant Human SPARCL1 protein |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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