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Anti-SPARCL1 Antibody-PE (7L739)

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产品编号 TMAY-00166P

Anti-SPARCL1 Antibody-PE (7L739) 是一种 PE-conjugated Rabbit 抗体,靶向 SPARCL1。Anti-SPARCL1 Antibody-PE (7L739) 可用于 FCM。

Anti-SPARCL1 Antibody-PE (7L739)

Anti-SPARCL1 Antibody-PE (7L739)

Rating icon 还可以
产品编号 TMAY-00166P

Anti-SPARCL1 Antibody-PE (7L739) 是一种 PE-conjugated Rabbit 抗体,靶向 SPARCL1。Anti-SPARCL1 Antibody-PE (7L739) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-SPARCL1 Antibody-PE (7L739) is a PE-conjugated Rabbit antibody targeting SPARCL1. Anti-SPARCL1 Antibody-PE (7L739) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
克隆号
7L739
交叉反应
Human
验证活性
Profile of anti-SPARCL1 reactivity on HL60 cells analyzed by flow cytometry.
应用
FCM
推荐剂量
5 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human SPARCL1 (rh SPARCL1; NP_004675.3Met 1-Phe 664) and conjugated with PE under optimum conditions, the unreacted PE was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景SPARC-like protein 1 (SPARCL1; also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins. It contains three conserved structural domains that are implicated in the regulation of cell adhesion, migration, and proliferation. SPARCL1 is expressed during embryogenesis and tissue remodeling and is especially prominent in brain and vasculature. Its down-regulation in a number of cancers and the possibility of its functional compensation by SPARC has led to recent interest in hevin as a tumor suppressor and regulator of angiogenesis. SPARCL1 has antiadhesive properties, and loss of SPARCL1 expression is associated with increased proliferative activity and cell cycle progression. It is suggested that it may influence multiple cellular processes during distinct stages of brain development and function. Besides, SPARCL1 can influence the function of astroglial cells in the developing and mature central nervous system (CNS).
偶联与修饰
偶联
PE
其他可选修饰符
Unconjugated/FITC
可提供抗体种类
3
抗原信息
免疫原
Recombinant Human SPARCL1 protein
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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