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顶部生物活性储存和溶解信息计算器

Anti-IKBKE Antibody (6N528)

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Anti-IKBKE Antibody (6N528)
产品编号 TMAC-02122
别名 MGC125297, MGC125295, MGC125294, KIAA0151, Inhibitor of nuclear factor kappa-B kinase subunit epsilon, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, epsilon, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase epsilon, Inducible IkappaB kinase, Inducible I kappa-B kinase, Inducible I kappa B kinase, IKK-i, IKKI, IKK-epsilon, IKKepsilon, IKKE_HUMAN, IKK-E, IKKE, IKK related kinase epsilon, IKBKε, IKBKepsilon, IkBKE, IKBK ε, IKBK epsilon, IKBK E, I-kappa-B kinase epsilon, I kappa B kinase epsilon

Anti-IKBKE Antibody (6N528) 是一种 Rabbit 抗体，靶向 IKBKE。Anti-IKBKE Antibody (6N528) 可用于 WB,ICC,FCM,IHC。

Anti-IKBKE Antibody (6N528)

Anti-IKBKE Antibody (6N528)

Rating icon 还可以
Anti-IKBKE Antibody (6N528)
产品编号 TMAC-02122 别名 MGC125297, MGC125295, MGC125294, KIAA0151, Inhibitor of nuclear factor kappa-B kinase subunit epsilon, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, epsilon, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase epsilon, Inducible IkappaB kinase, Inducible I kappa-B kinase, Inducible I kappa B kinase, IKK-i, IKKI, IKK-epsilon, IKKepsilon, IKKE_HUMAN, IKK-E, IKKE, IKK related kinase epsilon, IKBKε, IKBKepsilon, IkBKE, IKBK ε, IKBK epsilon, IKBK E, I-kappa-B kinase epsilon, I kappa B kinase epsilon

Anti-IKBKE Antibody (6N528) 是一种 Rabbit 抗体，靶向 IKBKE。Anti-IKBKE Antibody (6N528) 可用于 WB,ICC,FCM,IHC。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-IKBKE Antibody (6N528) is a Rabbit antibody targeting IKBKE. Anti-IKBKE Antibody (6N528) can be used in WB,ICC,FCM,IHC.
别名MGC125297, MGC125295, MGC125294, KIAA0151, Inhibitor of nuclear factor kappa-B kinase subunit epsilon, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, epsilon, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase epsilon, Inducible IkappaB kinase, Inducible I kappa-B kinase, Inducible I kappa B kinase, IKK-i, IKKI, IKK-epsilon, IKKepsilon, IKKE_HUMAN, IKK-E, IKKE, IKK related kinase epsilon, IKBKε, IKBKepsilon, IkBKE, IKBK ε, IKBK epsilon, IKBK E, I-kappa-B kinase epsilon, I kappa B kinase epsilon
Ig Type
IgG
克隆号
6N528
交叉反应
Human
验证活性
1. Western blot analysis of IKBKE on different cell lysates using anti-IKBKE antibody at 1/500 dilution. Positive control: Lane 1: Hela, Lane 2: Raji, Lane 3: MCF-7, Lane 4: Jurkat.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-IKBKE antibody. Counter stained with hematoxylin.
3. ICC staining IKBKE in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining IKBKE in JAR cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining IKBKE in SK-Br-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC
FCM
IHC
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The transcription factor NFκB is retained in the cytoplasm in an inactive form by the inhibitory protein IκB. Activation of NFκB requires that IκB be phosphorylated on specific serine residues, which results in targeted degradation of IκB. IκB kinase α (IKKα), previously designated CHUK, interacts with IκB-α and specifically phosphorylates IκB-α on the sites that trigger its degradation, Serines 32 and 36. The functional IKK complex contains three subunits, IKKα, IKKβ and IKKγ (also designated NEMO), and each appear to make essential contributions to IκB phosphorylation. IKK-i is a serine/threonine kinase that shares homology with IKKα and IKKβ. IKK-i is primarily expressed in immune cells and is induced by lipopolysaccharide and by proinflammatory cytokines including TNFα, IL-1 and IL-6. Overexpression of IKK-i has been shown to result in phosphorylation of IκBα on Ser 32 and Ser 36, and in NFκB activation, suggesting that IKK-i may act as an IκB kinase in the immune system.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q14164
化学信息
分子量Theoretical: 80 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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