购物车
- 全部删除
您的购物车当前为空
Anti-IL-6 Antibody (9P892)
还可以产品编号 TMAH-00626
别名 白细胞介素, Interleukin-6, interleukin 6, IL-6, IFNB2, HSF, HGF, BSF2
Anti-IL-6 Antibody (9P892) 是一种抗体，靶向 IL-6。Anti-IL-6 Antibody (9P892) 可用于 ELISA。
Anti-IL-6 Antibody (9P892)
Anti-IL-6 Antibody (9P892)
还可以产品编号 TMAH-00626 别名 白细胞介素, Interleukin-6, interleukin 6, IL-6, IFNB2, HSF, HGF, BSF2
Anti-IL-6 Antibody (9P892) 是一种抗体，靶向 IL-6。Anti-IL-6 Antibody (9P892) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IL-6 Antibody (9P892) is an antibody targeting IL-6. Anti-IL-6 Antibody (9P892) can be used in ELISA. |
| 别名 | 白细胞介素, Interleukin-6, interleukin 6, IL-6, IFNB2, HSF, HGF, BSF2 |
| Ig Type | Human IgG1 |
| 克隆号 | 9P892 |
| 交叉反应 | Human |
| 验证活性 | The Binding Activity of Human IL6 with Anti-IL6 Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL6 at 2 μg/mL can bind Anti-IL6 recombinant antibody. The EC50 is 35.80-41.82 ng/mL. |
| 应用 | ELISA |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury (Probable). In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells. Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability. Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF. Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance. 'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis. Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand. Also acts as a myokine (Probable). Plays a protective role during liver injury, being required for maintenance of tissue regeneration. Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection. Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human IL6 Protein |
| 抗原种属 | Human |
| 基因ID | 3569 |
| Uniprot ID | |
| 研究领域 | Neuroscience, Cancer, Immunology, Metabolism |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-IL-6 Antibody (9P892) | purchase Anti-IL-6 Antibody (9P892) | Anti-IL-6 Antibody (9P892) cost | order Anti-IL-6 Antibody (9P892)
嗨！有任何问题？点我咨询
评论内容