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顶部相关产品产品介绍化学信息储存和溶解信息计算器

FMAU

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纯度: 98.6%

货号 TNU0159Cas号 69256-17-3

别名 2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine

FMAU (2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine) is a thymine nucleoside analog with insertional activity on replicating DNA.FMAU can be used to label cells and track DNA synthesis.

FMAU

FMAU

一键复制产品信息
Rating icon 很棒

纯度: 98.6%

货号 TNU0159 别名 2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridineCas号 69256-17-3

FMAU (2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine) is a thymine nucleoside analog with insertional activity on replicating DNA.FMAU can be used to label cells and track DNA synthesis.

规格价格库存数量
25 mg
¥ 141
现货
50 mg
¥ 188
现货
100 mg
¥ 273
现货
200 mg
¥ 465
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产品介绍

FMAU AI Summary
FMAU exhibits potent antiviral activity against multiple strains of Herpes simplex virus (HSV) and Varicella zoster virus (VZV). Specifically, it shows efficacy against HSV-1(F) and HSV-2(G) with effective dose (ED50) values ranging from 0.013 uM to 0.023 uM and strong inhibition with ED90 values of 0.047 uM and 0.09 uM, respectively. Additionally, it demonstrates significant activity against the Varicella zoster virus with an ED50 of 0.02 uM in human foreskin fibroblasts. The compound also displays notable antihepatitis-B virus activity, with an EC50 of 100.0 nM in 2.2.15 cells and a high selectivity index greater than 2000. Despite its antiviral potency, FMAU exhibits moderate cytotoxicity on Vero cells and other rapidly dividing cell lines, with ID50 values indicating potential risks at higher concentrations. Overall, FMAU shows strong therapeutic potential for treating viral infections, particularly those caused by HSV and hepatitis B, though its cytotoxic effects warrant careful dosage management..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
FMAU (2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine) is a thymine nucleoside analog with insertional activity on replicating DNA.FMAU can be used to label cells and track DNA synthesis.
别名2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine
化学信息
分子量260.22
分子式C10H13FN2O5
CAS No.69256-17-3
SmilesCc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2F)c(=O)[nH]c1=O
颜色White
物理性状Solid
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度信息
DMSO: 50 mg/mL (192.15 mM), Sonication is recommended.
溶液配制表
DMSO
1mg5mg10mg50mg
1 mM3.8429 mL19.2145 mL38.4290 mL192.1451 mL
5 mM0.7686 mL3.8429 mL7.6858 mL38.4290 mL
10 mM0.3843 mL1.9215 mL3.8429 mL19.2145 mL
20 mM0.1921 mL0.9607 mL1.9215 mL9.6073 mL
50 mM0.0769 mL0.3843 mL0.7686 mL3.8429 mL
100 mM0.0384 mL0.1921 mL0.3843 mL1.9215 mL

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
TargetMol | Animal experiments 比如您的给药剂量是10 mg/kg，每只动物体重20g，给药体积100 μL， TargetMol | Animal experiments 一共给药动物10只，您使用的配方为5%TargetMol | reagent DMSO + 30%PEG300 + 5%Tween 80 + 60%Saline/PBS/ddH2O， 那么您的工作液浓度为2mg/mL。
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent （ 母液浓度为 40 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法: 取 50μLDMSOTargetMol | reagent 母液，添加 300 μLPEG300TargetMol | reagent 混匀澄清，再加 50μLTween80, 混匀澄清，再加 600μLSaline/PBS/ddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO ， PEG300 / PEG400 ， Tween 80 ， SBE-β-CD ， 玉米油 等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

FMAUDNA synthesisApoptosis2'-Deoxy-2'-fluoro-5-methyl-β-D-arabinouridine2'-Deoxy-2'-fluoro-5-methyl-b-D-arabinouridine
Related Tags: buy FMAU | purchase FMAU | FMAU cost | order FMAU | FMAU chemical structure | FMAU formula | FMAU molecular weight