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Anti-IL-1R1 Antibody (4O465)
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产品编号 TMAH-00618
别名 P80, interleukin 1 receptor, type I, IL-1R-α, IL-1R-alpha, IL1RA, IL-1R1, IL1R, IL-1 RI, D2S1473, CD121A
Anti-IL-1R1 Antibody (4O465) 是一种抗体，靶向 IL-1R1。Anti-IL-1R1 Antibody (4O465) 可用于 ELISA, FCM。
Anti-IL-1R1 Antibody (4O465)
Anti-IL-1R1 Antibody (4O465)
还可以产品编号 TMAH-00618 别名 P80, interleukin 1 receptor, type I, IL-1R-α, IL-1R-alpha, IL1RA, IL-1R1, IL1R, IL-1 RI, D2S1473, CD121A
Anti-IL-1R1 Antibody (4O465) 是一种抗体，靶向 IL-1R1。Anti-IL-1R1 Antibody (4O465) 可用于 ELISA, FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IL-1R1 Antibody (4O465) is an antibody targeting IL-1R1. Anti-IL-1R1 Antibody (4O465) can be used in ELISA, FCM. |
| 别名 | P80, interleukin 1 receptor, type I, IL-1R-α, IL-1R-alpha, IL1RA, IL-1R1, IL1R, IL-1 RI, D2S1473, CD121A |
| Ig Type | Mouse IgG2a |
| 克隆号 | 4O465 |
| 交叉反应 | Human |
| 验证活性 | Overlay Peak curve showing NIH/3T3 cells surface stained with TMAH-00618 (red line) at 1:50. Then 10% normal goat serum was Incubated to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45 min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| 应用 | |
| 推荐剂量 | FCM:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. Cell membrane. Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human IL1R1 Protein |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Cardiovascular, Immunology, Stem cells |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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