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ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase.

ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 10 mg | ¥ 7,650 | 35日内发货 |
ARL67156 trisodium salt 相关产品
| 产品描述 | ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase. |
| 靶点活性 | NTPDase3:18 μM(ki), NPP1:12 μM(ki), NTPDase1:(ki)11 μM |
| 体外活性 | ARL67156 is not an effective inhibitor of NTPDase2, NTPDase8, NPP3 and ecto-5′-nucleotidase (CD73). And It also reduces the activity of these enzymes[1]. ARL67156 trisodium salt is also an effective inhibitor of UTP breakdown by superior cervical ganglion cells and to potentiate contractions elicited by this nucleotide in isolated tail artery of rat. |
| 分子量 | 785.05 |
| 分子式 | C15H21Br2N5Na3O12P3 |
| CAS No. | 1021868-83-6 |
| 密度 | no data available |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| 溶解度信息 | H2O: 25 mg/mL (31.72 mM), Sonication is recommended. | |||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||
H2O
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