Name: ARL67156 trisodium salt
Brand: TargetMol
SKU: T14320
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

10 mg

¥ 7,650

35日内发货

生物活性

产品描述	ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase.
靶点活性	NTPDase3:18 μM(ki), NPP1:12 μM(ki), NTPDase1:（ki）11 μM
体外活性	ARL67156 is not an effective inhibitor of NTPDase2, NTPDase8, NPP3 and ecto-5′-nucleotidase (CD73). And It also reduces the activity of these enzymes[1]. ARL67156 trisodium salt is also an effective inhibitor of UTP breakdown by superior cervical ganglion cells and to potentiate contractions elicited by this nucleotide in isolated tail artery of rat.

化学信息

分子量	785.05
分子式	C₁₅H₂₁Br₂N₅Na₃O₁₂P₃
CAS No.	1021868-83-6
Smiles	[Na].[Na].[Na].CCN(CC)c1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)C(Br)(Br)P(O)(O)=O)[C@@H](O)[C@H]1OjcExt:v:0:0,1:0,2:0
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

H2O: 25 mg/mL (31.85 mM), Sonication is recommended.

溶液配制表

H2O