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Anti-CD27/TNFRSF7 Antibody (3U92)
还可以产品编号 TMAY-00141
Anti-CD27/TNFRSF7 Antibody (3U92) 是一种 Mouse 抗体，靶向 CD27/TNFRSF7。Anti-CD27/TNFRSF7 Antibody (3U92) 可用于 FCM。
Anti-CD27/TNFRSF7 Antibody (3U92)
Anti-CD27/TNFRSF7 Antibody (3U92)
还可以产品编号 TMAY-00141
Anti-CD27/TNFRSF7 Antibody (3U92) 是一种 Mouse 抗体，靶向 CD27/TNFRSF7。Anti-CD27/TNFRSF7 Antibody (3U92) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-CD27/TNFRSF7 Antibody (3U92) is a Mouse antibody targeting CD27/TNFRSF7. Anti-CD27/TNFRSF7 Antibody (3U92) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3U92 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CD27 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD27, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD27 (rh CD27; NP_001233.1Met1-Ile192). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/PerCP/FITC/PE |
| 可提供抗体种类 | 5 |
| 免疫原 | Recombinant Human CD27 Protein |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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