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Anti-NGF Antibody (1V140) 是一种 Mouse 抗体,靶向 NGF。Anti-NGF Antibody (1V140) 可用于 ELISA。
Anti-NGF Antibody (1V140) 是一种 Mouse 抗体,靶向 NGF。Anti-NGF Antibody (1V140) 可用于 ELISA。
产品描述 | Anti-NGF Antibody (1V140) is a Mouse antibody targeting NGF. Anti-NGF Antibody (1V140) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 1V140 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NGF / NGFB (rh NGF / NGFB; TMPY-01010; NP_002497.2; Ser122-Arg239). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system. |
偶联 | Unconjugated |
免疫原 | Recombinant Human NGF / NGFB protein (TMPY-01010) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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