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Anti-Phospho-Tuberin (Thr1462) Polyclonal Antibody 2
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还可以产品编号 TMAB-11403
Anti-Phospho-Tuberin (Thr1462) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Tuberin (Thr1462)。Anti-Phospho-Tuberin (Thr1462) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。
Anti-Phospho-Tuberin (Thr1462) Polyclonal Antibody 2
Anti-Phospho-Tuberin (Thr1462) Polyclonal Antibody 2
一键复制产品信息 还可以产品编号 TMAB-11403
Anti-Phospho-Tuberin (Thr1462) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Tuberin (Thr1462)。Anti-Phospho-Tuberin (Thr1462) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
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| 产品描述 | Anti-Phospho-Tuberin (Thr1462) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Tuberin (Thr1462). Anti-Phospho-Tuberin (Thr1462) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 交叉反应 | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| 应用 | IHC-PIHC-FrIFFCM |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 2μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Membrane; Peripheral membrane protein. Note=At steady state found in association with membranes. |
| 组织特异性 | Liver, brain, heart, lymphocytes, fibroblasts, biliary epithelium, pancreas, skeletal muscle, kidney, lung and placenta. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human Tuberin around the phosphorylation site of Thr1462 |
| 抗原种属 | Human |
| 基因名称 | TSC2 |
| 基因ID | |
| 蛋白名称 | Tuberin |
| Uniprot ID | |
| 功能 | In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. Stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro. Mutations in TSC2 lead to constitutive activation of RAP1A in tumors. |
| 分子量 | Theoretical: 200 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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