IL-15RA Protein, Mouse, Recombinant (hFc)（Human Cells）

Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.

规格	价格/CNY		数量
10 μg	￥ 380	现货
20 μg	￥ 530	5日内发货
50 μg	￥ 810	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 380

现货

20 μg

￥ 530

5日内发货

50 μg

￥ 810

5日内发货

生物活性

Measured by its ability to block human IL-15-induced proliferation of CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.5-2 ng/ml. (QC verified)

TargetMol Bioactive

产品描述

种属	Mouse
表达系统	Human Cells
标签	C-Fc
蛋白编号	Q60819
别名	sIL-15 receptor subunit α, Il15ra, Interleukin-15 receptor subunit alpha, Interleukin-15 receptor subunit α, sIL-15 receptor subunit alpha
氨基酸序列	Gly33-Lys205
蛋白构建	Recombinant Mouse Interleukin-15 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Gly33-Lys205 is expressed with a human IgG1 Fc tag at the C-terminus.
分子量	60-90 KDa, reducing conditions

内毒素	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶方法	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
存储	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
研究背景	Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.

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IL-15RA Protein, Mouse, Recombinant (hFc)（Human Cells）

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