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IL-15RA Protein, Mouse, Recombinant (hFc)

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货号 TMPJ-00154

别名 sIL-15 receptor subunit α, sIL-15 receptor subunit alpha, Interleukin-15 receptor subunit α, Interleukin-15 receptor subunit alpha, Il15ra

Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.

IL-15RA Protein, Mouse, Recombinant (hFc)
其他形式的 “IL-15RA Protein, Mouse, Recombinant (hFc)”:
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
IL-15RA Protein, Human, Recombinant (His & Avi)
IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated
IL-15RA Protein, Human, Recombinant (aa 31-205, hFc)
IL-15RA Protein, Human, Recombinant (His)
IL-15RA Protein, Human, Recombinant (hFc & Avi), Biotinylated

IL-15RA Protein, Mouse, Recombinant (hFc)

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货号 TMPJ-00154 别名 sIL-15 receptor subunit α, sIL-15 receptor subunit alpha, Interleukin-15 receptor subunit α, Interleukin-15 receptor subunit alpha, Il15ra

Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.

规格价格库存数量
5 μg
¥ 243
3日内发货
10 μg
¥ 380
现货
20 μg
¥ 530
5日内发货
50 μg
¥ 810
5日内发货
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产品介绍

生物活性
产品描述
Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.
生物活性
Measured by its ability to block human IL-15-induced proliferation of CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.5-2 ng/ml. (QC verified)
IL-15RA Protein, Mouse, Recombinant (hFc)
研究背景
Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.
种属
Mouse
表达系统
HEK293 Cells
标签C-hFc
蛋白编号Q60819
氨基酸序列Gly33-Lys205
蛋白构建Gly33-Lys205
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名sIL-15 receptor subunit α, sIL-15 receptor subunit alpha, Interleukin-15 receptor subunit α, Interleukin-15 receptor subunit alpha, Il15ra
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量60-90 KDa (reducing condition)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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