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Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi)

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货号 TMPK-00283

别名 RCC, PMW1, P54/58N, MN, G250, EC 4.2.1.1, Carbonic Anhydrase IX, CA-IX, CAIX, CA9

CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways. CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 43.7 kDa and the accession number is Q16790.

Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi)

Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi)

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货号 TMPK-00283 别名 RCC, PMW1, P54/58N, MN, G250, EC 4.2.1.1, Carbonic Anhydrase IX, CA-IX, CAIX, CA9

CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways. CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 43.7 kDa and the accession number is Q16790.

规格价格库存数量
5 μg
¥ 373
6-8日内发货
10 μg
¥ 598
6-8日内发货
20 μg
¥ 983
5日内发货
50 μg
¥ 1,930
5日内发货
100 μg
¥ 3,250
5日内发货
200 μg
¥ 5,890
5日内发货
500 μg
¥ 13,000
5日内发货
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产品介绍


生物活性
产品描述
CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways. CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 43.7 kDa and the accession number is Q16790.
生物活性
Immobilized Human CA9, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Anti-CA9 Antibody, hFc Tag with the EC50 of 8.0ng/ml determined by ELISA.
研究背景
CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways.
种属
Human
表达系统
HEK293 Cells
标签C-His-Avi
蛋白编号Q16790
蛋白构建Gln38-Asp414
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 150 mM NaCl (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名RCC, PMW1, P54/58N, MN, G250, EC 4.2.1.1, Carbonic Anhydrase IX, CA-IX, CAIX, CA9
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量43.7 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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